Mission Meets Metrics: Ryan Dewey Smith’s Blueprint for Nonprofit Growth

Ryan Dewey Smith
Ryan Dewey Smith, Founding Executive Chairman and Chief Executive Officer of Inperium, Inc., that has helped dozens of organizations move beyond survival into sustainable expansion joins Enterprise Radio.

Listen to host Eric Dye & guest Ryan Dewey Smith discuss the following:

  1. Ryan, when people hear ‘nonprofit,’ they often picture something scrappy and under-resourced. You’ve clearly rejected that image. What’s the biggest myth about running a mission-driven organization that you’d want every listener to unlearn today?
  2. For listeners who run a nonprofit or mission-driven organization and feel stuck in ‘survival mode’ where they are always chasing the next grant or donation, what’s one shift in mindset or strategy that could get them thinking more like a growth-oriented business?
  3. You’ve talked about applying startup thinking to mission-driven work. If someone’s listening right now and wants to bring more of that entrepreneurial energy into their organization, what’s a practical first step, something they could try this week?
  4. What’s a metric or way of measuring success that most nonprofits overlook, but that you think should be front and center?
  5. For the entrepreneurs listening who are trying to build a team that’s just as passionate about the mission as they are—how do you approach hiring and culture-building differently than a typical nonprofit might?
  6. If you could go back and give yourself one piece of advice at the very beginning of this journey, something that would’ve saved you time, money, or headaches, what would it be?

Ryan Dewey Smith is the Founding Executive Chairman and Chief Executive Officer of Inperium, Inc., one of the largest nonprofit orchestrators and consolidators of health and human services providers in the United States. Under his leadership, Inperium has pioneered a new model of nonprofit stewardship that preserves the independence of its affiliates while delivering scale, efficiency, and capital strength. Ryan is a trusted innovator, thought leader, and author with more than three decades of experience in nonprofit growth and transformation. His forthcoming book, Sustaining the Mission, to be published by Forbes in September 2026, chronicles Inperium’s journey and offers a roadmap for nonprofits seeking lasting resilience without sacrificing the autonomy that makes their work meaningful.

Website: ryandeweysmith.com
Linkedin: linkedin.com/in/ryan-dewey-smith


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